Supervisor, IgG Production

1 hour, 27 minutes ago
Full-time
Senior
Operations
Twist Bioscience

Twist Bioscience

Twist Bioscience is a leading synthetic biology company offering innovative silicon-based DNA synthesis and a range of high-quality synthetic DNA tools to accelerate research and drive positive change globally.

Pharmaceuticals
251-1K
Founded 2013

Description

  • Manufacture high-quality custom IgG products according to established SOPs in a high-throughput manufacturing lab.
  • Plan, prioritize, and troubleshoot production orders with the manufacturing team.
  • Manage, train, and mentor manufacturing associates and shift operators.
  • Track product quality metrics using physical and functional test methods.
  • Summarize production progress, issues, and timelines for upper management.
  • Apply scientific understanding to troubleshoot test results and production problems.
  • Identify opportunities to improve lab techniques, protocols, processes, equipment handling, and overall workflow.
  • Maintain equipment, including calibration of select lab instruments, and uphold safe working practices.
  • Lead shift pass-downs, coordinate staffing schedules, and ensure continuity between shifts.
  • Review batch records and manufacturing documents, and write incident reports, CAPAs, and planned deviations.

Requirements

  • A.S. or B.S. in Biology, Chemistry, or Biochemistry.
  • 2-5 years of laboratory experience in a manufacturing environment.
  • Experience leading small teams within a laboratory setting.
  • Experience with traditional molecular biology techniques, especially sterile cell culture, antibody quantitation and purification, DNA extraction, and sample handling.
  • Knowledge of basic synthetic/molecular biology workflows, including mammalian cell culturing, MiniPrep, transfection, buffer exchange, and CE preparation.
  • Experience operating liquid handlers such as Hamilton and Tecan systems is highly desirable.
  • Experience with sample tracking software and integrating robotic instrumentation with LIMS/MES systems.
  • Experience working in ISO, GMP, or LEAN manufacturing environments.
  • Excellent scientific computation and data analysis skills.
  • Ability to stand for long periods, work safely with chemicals and hazardous materials, lift up to 20 lbs, and work flexible or outside regular hours as needed.

Benefits

  • Equal employment opportunities for all employees and applicants regardless of protected characteristics.
  • Opportunity to work on Twist Bioscience’s proprietary DNA synthesis and antibody manufacturing platform.
  • Work in a highly automated, high-throughput, LEAN-controlled laboratory environment.

Interested in this position?

Apply directly on the company website

Apply Now

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