Natera

Natera specializes in cell-free DNA testing, providing advanced genetic testing services for oncology, women's health, and organ health to help families diagnose and manage genetic diseases.

Pharmaceuticals

Health Care

1K-5K (2670)

Founded 2004

56 open positions

Links

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Principal Software Engineer

1 hour, 45 minutes ago

United States

Full-time

Lead

Software Engineer

Software Development

AWS CI/CD DynamoDB Generative AI Java Kafka MySQL Next.js PostgreSQL Python React SQL TypeScript

Apply Now

Natera

Natera specializes in cell-free DNA testing, providing advanced genetic testing services for oncology, women's health, and organ health to help families diagnose and manage genetic diseases.

Pharmaceuticals

1K-5K

Founded 2004

View All Jobs 56

Description

Own and evolve the architecture of large-scale, mission-critical systems for lab automation, workflow orchestration, and decision support.
Define and enforce architectural patterns for modular, distributed systems and modernize legacy LIMS platforms to cloud-native architectures.
Make technical decisions that balance scalability, reliability, security, cost, and regulatory constraints.
Establish engineering best practices across performance, observability, testing, security, and operational readiness.
Mentor senior engineers and managers through design reviews, technical guidance, and reusable frameworks.
Drive adoption of Generative AI to improve developer productivity and software quality.
Lead the application of AI/ML capabilities to improve lab throughput, turnaround time, automation reliability, and operator experience.
Lead the full software development lifecycle from problem framing and architecture through implementation, deployment, and production support.
Plan and execute complex migrations from legacy lab systems to a new strategic platform, including data migration, integration cutovers, validation, and rollback planning.
Build and review backend services and modern frontend applications using Python, TypeScript, React, and Next.js.

Requirements

12-15+ years of experience developing software applications.
Proven experience with Python, Java, Next.js, and TypeScript.
Solid understanding of relational databases and SQL, with a preference for MySQL or PostgreSQL.
Solid understanding of non-relational and graph databases.
Proficiency with AWS services including Lambda, RDS, DynamoDB, S3, and Glue.
Proficiency in infrastructure as code (IaC).
Proficiency with messaging frameworks such as Kafka.
Strong quality assurance mindset focused on robust and reliable software.
Excellent problem-solving skills and the ability to work independently and collaboratively in a dynamic environment.
Strong written and verbal communication skills with excellent interpersonal skills.
Experience building custom Laboratory Information Management Systems (LIMS) or Laboratory Execution Systems (LES) is preferred.
Experience with lab equipment and lab automation is preferred.

Benefits

Base pay range of $186,200 to $232,800 USD for Austin, TX.
Comprehensive medical, dental, vision, life, and disability coverage for eligible employees and dependents.
Free testing for employees and their immediate families.
Fertility care benefits.
Pregnancy and baby bonding leave.
401(k) benefits.
Commuter benefits.
Generous employee referral program.

Interested in this position?

Apply directly on the company website

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