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Molecular Biology Expert

1 month, 1 week ago
United Kingdom
Part-time
Lead
AI (Artificial Intelligence)
Artificial Intelligence and Machine Learning
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Weekday helps companies hire engineers who are vouched by other software engineers, enabling passive income for engineers. They offer services like drafting outreach messages, shortlisting candidates, and conducting reference checks. Backed by Y Combin...

Construction & Engineering
11-50
Founded 2020
View All Jobs 154

Description

  • Design and review DNA and RNA constructs, including primers, plasmids, expression vectors, CRISPR guide RNAs, mRNA constructs, and HDR or repair templates.
  • Create challenging, scientifically accurate molecular biology design tasks and develop detailed reference solutions.
  • Evaluate AI-generated molecular biology solutions for scientific accuracy, experimental feasibility, and biological reasoning.
  • Provide structured written feedback to improve AI performance in nucleic acid sequence design and molecular biology workflows.
  • Justify sequence-level design decisions such as guide RNA selection, target specificity, homology arm design, primer Tm optimization, codon optimization, and regulatory element selection.
  • Apply cloning expertise in Gibson Assembly, Golden Gate Assembly, Gateway Cloning, and restriction enzyme-based cloning.
  • Collaborate with fellow subject matter experts to ensure consistency, quality, and scientific rigor across AI training datasets.

Requirements

  • Hands-on experience designing nucleic acid constructs for molecular biology experiments, including primers, plasmids, expression vectors, CRISPR gRNA/sgRNA, mRNA or RNA constructs, and HDR or repair templates.
  • Strong understanding of cloning methodologies, including Gibson Assembly, Golden Gate Assembly, Gateway Cloning, and traditional restriction cloning.
  • Experience with codon optimization, vector design, and sequence engineering.
  • Advanced degree in Molecular Biology, Genetics, Biochemistry, Synthetic Biology, Bioengineering, or a related life sciences discipline; PhD is strongly preferred.
  • Strong peer-reviewed publication record, with first-author publications in leading scientific journals highly desirable.
  • Excellent written communication skills with the ability to clearly explain molecular biology design decisions and scientific reasoning.
  • Ability to work independently while maintaining exceptional scientific accuracy and attention to detail.
  • Research experience in genome editing, synthetic biology, functional genomics, or gene therapy is preferred.
  • Publications in high-impact journals such as Nature, Cell, eLife, Nucleic Acids Research, PNAS, or EMBO Journal are preferred.
  • Experience mentoring researchers or reviewing scientific work is preferred.

Benefits

  • Compensation of $70-$105 per hour.
  • Fully remote work with flexible scheduling.
  • Part-time to full-time engagement of up to 40 hours per week.
  • Opportunity to contribute to an initial cohort focused on designing and evaluating molecular biology tasks.
  • Potential for extended engagement as project needs evolve for high-performing contributors.

Interested in this position?

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