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Associate Director, Bioinformatics Development

1 month, 2 weeks ago
United States
Full-time
Lead
Data Scientist
Software Development
AWS EC2 Python R
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Veracyte

Veracyte

Veracyte develops innovative molecular diagnostic tests that provide clinicians with critical insights to enhance cancer diagnosis and treatment, ultimately aiming to improve patient outcomes and reduce healthcare costs.

Pharmaceuticals
251-1K
Founded 2008
View All Jobs 12

Description

  • Lead bioinformatics strategy, design, and development for one or more MRD assay programs.
  • Provide technical leadership and mentorship to computational development scientists and bioinformatics team members.
  • Partner with wet-lab, clinical, quality, regulatory, and software teams to deliver analytically robust diagnostics.
  • Guide assay architecture, signal detection strategies, error suppression approaches, and MRD calling methodologies.
  • Lead or oversee analytical study design and data analysis for assay development and validation.
  • Develop, validate, and maintain scalable, production-ready bioinformatics pipelines for MRD analysis, QC, and reporting.
  • Review and approve analytical approaches, benchmarking studies, and optimization strategies.
  • Ensure compliance with CAP/CLIA, FDA, and IVDR requirements across the development lifecycle.
  • Support career development through coaching, technical review, and knowledge sharing.
  • Communicate complex analytical concepts to stakeholders and senior leadership.

Requirements

  • Ph.D. in Bioinformatics, Computational Biology, Genomics, Biostatistics, or a closely related quantitative field.
  • 8+ years of total relevant experience, including at least 5 years of management experience in biotech, diagnostics, or regulated healthcare.
  • Experience leading NGS-based clinical assay development, with hands-on ctDNA-based MRD assay experience, including personalized or tumor-informed approaches.
  • Strong Python programming skills with experience building and benchmarking reproducible, production-grade analysis pipelines.
  • Experience with SDLC best practices.
  • Proven experience working in design-controlled, regulated environments such as CAP/CLIA LDT, IVD, or equivalent.
  • Experience collaborating with wet-lab scientists on iterative experiment design, execution, analysis, and interpretation.
  • Demonstrated technical and scientific leadership, ownership, and independent work.
  • Experience deploying bioinformatics workflows in AWS, such as EC2, S3, Step Functions, Batch, and Lambda, is preferred.
  • Working knowledge of R is preferred.
  • Experience with relational and non-relational database technologies is a plus.
  • Strong understanding of germline and somatic mutation processes and genome-wide biomarkers with potential clinical utility is preferred.

Benefits

  • Base salary range of $202,000-$219,000 for San Diego, $220,000-$231,000 for South San Francisco, or $192,000-$208,000 for remote US candidates.
  • Eligibility for additional discretionary bonuses and incentives.
  • Restricted stock units may be offered as part of the total package.
  • Competitive compensation and benefits.
  • Flexible work options including onsite, hybrid, or remote (US).
  • Opportunity to work in an inclusive, purpose-driven environment recognized as a 2024 Certified Great Place to Work®.
  • Career growth and development opportunities within a growing company.

Interested in this position?

Apply directly on the company website

Apply Now

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