Director, Translational Sciences

3 weeks, 4 days ago
Full-time
Lead
Project and Program Management
Natera

Natera

Natera specializes in cell-free DNA testing, providing advanced genetic testing services for oncology, women's health, and organ health to help families diagnose and manage genetic diseases.

Pharmaceuticals
1K-5K
Founded 2004

Description

  • Lead external pre-clinical research through CRO and academic partnerships for functional validation, including immunogenicity, mechanism-of-action, and T-cell assays.
  • Define experimental strategies and governance frameworks, including statements of work, budgets, and partner performance management.
  • Direct immune functional assays and validate targets and biomarkers identified by AI/ML platforms using patient-derived samples.
  • Incorporate high-throughput screening to validate drug-target interactions and ensure data packages meet internal, regulatory, and clinical translation standards.
  • Partner with R&D, Clinical Development, and Regulatory teams to align assay outputs with program milestones.
  • Build a scalable external network across immunology and tumor biology while developing a roadmap for internal wet-lab capabilities.
  • Deliver data-backed updates and actionable recommendations to leadership.
  • Mentor scientific staff and contractors as the function scales.

Requirements

  • PhD, or equivalent, in Immunology, Biology, Pharmacology, or a related field, with 8+ years of post-graduate experience in biotech, pharma, or translational academic settings.
  • MS with 12+ years of directly relevant experience.
  • Proven track record of managing complex external research programs.
  • Proven ability to build translational research capabilities.
  • Deep expertise in immuno-oncology, immune functional assays, and mechanistic evaluation.
  • Experience with high-dimensional data, such as single-cell sequencing, to validate AI-driven insights.
  • Track record leading externalized R&D through CROs, including governance, experimental design, and milestone delivery.
  • Strong project management skills across scoping, budgeting, and risk management for parallel studies.
  • Experience with assay development, transfer, and reproducibility best practices.
  • Clear communication skills to influence cross-functional teams and external partners.
  • Preferred: expertise in neoantigen biology, antigen presentation validation, or tumor model systems.

Benefits

  • Remote USA role.
  • Base pay range of $171,600 to $214,500 USD.
  • Comprehensive medical, dental, vision, life, and disability coverage for eligible employees and dependents.
  • Free testing for employees and their immediate families, plus fertility care benefits.
  • Pregnancy and baby bonding leave.
  • 401(k) benefits.
  • Commuter benefits.
  • Employee referral program.

Interested in this position?

Apply directly on the company website

Apply Now

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