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Scientist II, Display Technologies

18 minutes ago
United States
Full-time
Mid Level
Research Scientist
Artificial Intelligence and Machine Learning
Assembly Machine Learning Python R
Apply Now
xaira.com

xaira.com

Xaira is a company that specializes in domain sales and acquisitions. They believe in the value of a good domain name and help businesses acquire the right domain to showcase their responsibility and financial capability.

Internet Software & Services
View All Jobs 2

Description

  • Independently design, execute, and own phage display campaigns from library through panning and hit validation.
  • Develop and optimize selection strategies for difficult target classes, including troubleshooting antigen production, presentation, and quality control.
  • Design and build display libraries using cloning, mutagenesis, and assembly to generate diverse repertoires.
  • Run clonal-level affinity and functional characterization assays such as FACS, ELISA, and SPR, and adapt them for higher-throughput formats.
  • Partner with computational and machine learning colleagues to generate, structure, and quality-control data at scale.
  • Mentor associate scientists on display workflows, experimental design, and lab best practices.
  • Contribute to technical standards within the group.
  • Prepare technical reports, presentations, and documentation of methods and results.

Requirements

  • PhD in Molecular Biology, Biochemistry, Immunology, Protein Engineering, or a related field.
  • 2–4 years of relevant industry experience.
  • Significant hands-on expertise with antibody or protein discovery by phage display, including library design, build, panning/selection, and hit validation.
  • Strong molecular biology skills for library construction, including cloning, mutagenesis, and assembly.
  • Hands-on flow cytometry (FACS) experience, including data interpretation and gating strategy.
  • Experience running campaigns independently and troubleshooting challenging targets.
  • Experience with membrane proteins such as GPCRs in cell-based expression systems or recombinant formats is strongly preferred.
  • Strong working knowledge of antibody binding and characterization assays such as ELISA.
  • Proficiency in core molecular and cell biology techniques, including mammalian cell culture.
  • Excellent analytical, problem-solving, written, and verbal communication skills.
  • Ability to work collaboratively in a multidisciplinary team and support junior colleagues.
  • Experience with label-free affinity characterization such as SPR or BLI/Octet is a plus.
  • Experience with alternative display formats such as yeast, mammalian, or ribosome/mRNA display is a plus.
  • Experience with lab automation such as Hamilton or Tecan is a plus.
  • Working knowledge of scripting for large dataset analysis such as Python or R is a plus.

Benefits

  • Competitive compensation and benefits package.
  • Base salary range of $124,000 to $155,000 annually.
  • Bonus eligibility.
  • Equity package.
  • Open, flexible, and friendly work environment.
  • Support for long-term career development.
  • Summary of Benefits available to applicants.

Interested in this position?

Apply directly on the company website

Apply Now

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