Senior Scientist, Machine Learning

2 hours, 51 minutes ago
Full-time
Senior
Data Science and Analytics
Flagship Pioneering

Flagship Pioneering

Flagship Pioneering is a biotechnology firm that invents and develops innovative life science platforms and companies aimed at transforming human health and promoting sustainability.

Biotechnology
251-1K
Founded 1999

Description

  • Lead technology development aligned with FL129’s core scientific and strategic goals.
  • Develop, train, validate, and apply generative chemistry and molecular models.
  • Curate training and benchmark datasets for model development and evaluation.
  • Design and implement rigorous benchmarks to assess model performance.
  • Optimize existing workflows and establish experimental and documentation best practices.
  • Collaborate closely with the wet lab scientific team to advance key project goals.
  • Translate experimental data into actionable insights and present findings at team meetings.
  • Help influence the company’s scientific direction as an early hire.

Requirements

  • Ph.D. in machine learning, computational biology, or a similar field.
  • 5+ years of industry or postdoctoral experience.
  • Strong track record of scientific and technical innovation in machine learning for molecular modeling of proteins and/or small molecule ligands.
  • Experience with computational docking methods is preferred.
  • Familiarity with SOTA models such as Boltz-2, ESM-2, Chai-2, and related tools.
  • Experience training and fine-tuning molecular models for protein language modeling, protein structure prediction, binder prediction, protein design, protein engineering, small molecule pose prediction, or related tasks.
  • Experience curating publicly available datasets, including mutational scanning data.
  • Expertise with Python or another high-level programming language and modern HPC and cloud compute workflows.
  • Strong organizational skills and written/verbal communication skills.
  • Comfort working in a dynamic, cross-functional, and highly collaborative environment.

Benefits

  • Salary range of $168,000 - $258,500.
  • Healthcare coverage.
  • Annual incentive program.
  • Retirement benefits.
  • Opportunity to be an early employee helping build a transformative platform company.
  • Custom-tailored role to maximize impact, growth, and scientific interests.
  • Weekly lunches, monthly social events, and free snacks and coffee in a community setting.

Interested in this position?

Apply directly on the company website

Apply Now

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